Spruce Biosciences

Crinetics

This pharmaceutical company develops oral therapeutics for patients with rare endocrine diseases and endocrine-related tumours.

Amolyt Pharma

This clinical-stage biopharmaceutical company develops therapeutic peptides to treat patients with rare endocrine and related diseases, including hypoparathyroidism and acromegaly.

Septerna, Inc

This biotechnology company develops small-molecule medicines targeting G protein-coupled receptors to treat patients with endocrine, inflammatory and metabolic diseases.

Allievex

This clinical-stage biotechnology company develops enzyme replacement therapies for children with rare pediatric neurodegenerative diseases, specifically Sanfilippo syndrome type B.

Nitrase Therapeutics

This biopharmaceutical company develops enzyme-targeting therapies for patients with Parkinson's disease, cancer, and other age-related conditions.

Edgewise

This biopharmaceutical company develops oral small molecule therapies to treat patients with rare skeletal and cardiac muscle diseases.

Spur Therapeutics

This company develops adeno-associated virus gene therapies to treat chronic conditions including Gaucher disease and Parkinson's disease for patients with inherited genetic disorders.

Actio Biosciences

This biotechnology company develops small molecule medicines to treat rare genetic diseases and common conditions for patients with high unmet medical needs.